Matthew McConaughey and Woody Harrelson are Brothers in the trailer for the new comedy show

Apple TV unveiled the trailer for “Brothers,” the new comedy series starring and executive produced by Academy Award winner Matthew McConaughey and Academy Award nominee Woody Harrelson, and showrun and executive produced by multi-Emmy Award nominee and Peabody winner Lee Eisenberg. The eight-episode comedy will premiere on Apple TV with the first two episodes on Wednesday, September 23, followed by one new episode every Wednesday through November 4, 2026.

“Brothers” follows McConaughey and Harrelson, who play fictionalized versions of themselves, and whose friendship is thrown into chaos when they uncover a decades-old secret: they might actually be brothers. After Woody’s daughter’s engagement falls apart, he loads up the family and heads to Austin for an extended stay at Matthew’s ranch. But what begins as a healing getaway quickly spirals when Matthew’s mother, Ma Mac (played by Holland Taylor), accidentally lets slip a long-buried secret that the two friends might actually be brothers. As Woody turns the ranch upside down in pursuit of the truth, Matthew finds himself juggling an entirely different identity crisis: a potential run for Governor of Texas. The result is a heartfelt, chaotic, and wildly funny story about friendship, family, fame, and the messy line between myth and reality.

The ensemble cast starring alongside Harrelson and McConaughey includes Natalie Martinez, Brittany Ishibashi, Nolan Almeida, Ella Grace Helton, Noah Carganilla, Highdee Kuan, Oona Yaffe and Holland Taylor.

“Brothers” is produced for Apple TV by Paramount Television Studios. Eisenberg, McConaughey and Harrelson executive produce alongside Natalie Sandy, David West Read, Trish Hofmann, Bill Bost, Jason Winer, David Finkel & Brett Baer and Jeremy Plager. Trent O’Donnell directs multiple episodes including the pilot.