Watch Glenn Howerton in a first-look preview and trailer of A.P. Bio

From Executive Producers Seth Meyers and Lorne Michaels comes A.P. Bio, a new comedy starring Glenn Howerton (It’s Always Sunny in Philadelphia) and Patton Oswalt about a high school teacher who won’t be doing much teaching.

When disgraced Harvard philosophy scholar Jack Griffin (Glenn Howerton) loses out on his dream job, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement Biology teacher. As he comes crashing into Whitlock High School, Jack makes it absolutely clear he will not be teaching any biology. Realizing he has a room full of honor roll students at his disposal, Jack decides instead to use the kids for his own benefit. Eager to prove that he is still king of the castle, Principal Durbin (Patton Oswalt) struggles to control the force of nature that is Jack Griffin.

The show also stars Mary Sohn, Lyric Lewis, Jean Villepique, Jacob McCarthy, Tom Bennett, Paula Pell, Charlie McCrackin, Jacob McCarthy, Aparna Brielle, Nick Peine, Allisyn Ashley Arm, Eddie Leavy, Jacob Houston, Sari Arambulo, Tucker Albrizzi, and Spence Moore II.

Watch a special preview, Thursday, Feb 1 at 9:30/8:30c on NBC and the series begins on 1st March 2018.