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Kelly Macdonald, Rebecca Hall, and Rob Brydon join Holmes & Watson

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Will Ferrell and John C. Reilly have worked together on many things, including Step Brothers and Talladega Nights: The Ballad of Ricky Bobby. They are set to work together again as Sherlock Holmes and Dr. Watson.

Ferrell will play the great detective while Reilly will take on the role of sidekick John Watson in the comedy Holmes & Watson.

Kelly Macdonald, Rebecca Hall,
and Rob Brydon have also been cast in the film. Macdonald has been cast as Mrs. Hudson the housekeeper at 221B Baker Street, while Brydon will play Scotland Yard head Inspector Lestrade. Hall is set as Dr. Grace Hart, the first female doctor to practice in London. The join Lauren Lapkus, who will play a potential love interest for Ferrell.

Etan Cohen, who directed Ferrell in Get Hard, wrote the script and is set to direct the project for Sony. He also wrote the screenplays for Tropic Thunder, Men in Black 3 and Madagascar: Escape 2 Africa.

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